Source

Monoclonal Anti-RSV Antibody, Mouse IgG1 (11F6) is a Mouse monoclonal antibody expressed from HEK293 

Clone

11F6

Isotype

Mouse IgG1

Conjugate

Unconjugated

Antibody Type

Recombinant Monoclonal

Reactivity

Virus

Immunogen

Human respiratory syncytial virus (RSV) (A2) Prefusion glycoprotein F

Specificity

This product is a specific antibody specifically reacts with RSV virus.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A purified / Protein G purified

Formulation

Supplied as a 0.22 μm filtered solution of  PBS, pH7.4

Application

Application   Recommended Usage

ELISA             10~1000ng/mL

Storage

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Avoid repeated freeze-thaw cycles. 

SDS-PAGE

 11F6

RSV monoclonal antibody(11F6) on SDS-PAGE under reducing (R) and Non-reducing (N-R) condition.

The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%

 

Bioactivity-ELISA

11F6曲线

Immobilized RSV Fusion glycoprotein F,at 1μg/mL (100 μL/well) . Binding activity of RSV antibodies.

 

Background

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation.

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