Respiratory Syncytial Virus (RSV)monoclonal antibody (7A3)
Source
Monoclonal Anti-RSV Antibody, Mouse IgG1 (7A3) is a Mouse monoclonal antibody expressed from HEK293
Clone
7A3
Isotype
Mouse IgG1
Conjugate
Unconjugated
Antibody Type
Recombinant Monoclonal
Reactivity
Virus
Immunogen
Human respiratory syncytial virus (RSV) (A2) Prefusion glycoprotein F
Specificity
This product is a specific antibody specifically reacts with RSV virus.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A purified / Protein G purified
Formulation
Supplied as a 0.22 μm filtered solution of PBS, pH7.4
Application
Application Recommended Usage
ELISA 10~1000ng/mL
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Avoid repeated freeze-thaw cycles.
SDS-PAGE
RSV monoclonal antibody(7A3) on SDS-PAGE under reducing (R) and Non-reducing (N-R) condition.
The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
Bioactivity-ELISA
Immobilized RSV Fusion glycoprotein F,at 1μg/mL (100 μL/well) . Binding activity of RSV antibodies.
Background
Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation.