Influenza A monoclonal antibody(6A11)
Source
Monoclonal Anti-Influenza A Antibody, Mouse IgG1 (6A11) is a Mouse monoclonal antibody expressed from HEK293
Clone
6A11
Isotype
Mouse IgG1
Conjugate
Unconjugated
Antibody Type
Recombinant Monoclonal
Reactivity
Virus
Immunogen
Influenza A H1N1 (A/Wisconsin/67/2022) Nucleoprotein/NP
Specificity
This product is a specific antibody specifically reacts with Influenza A Nucleoprotein (Influenza A Virus).
Cross Verification
This product No cross-reactivity in ELISA with Influenza B (B/Austria/1359417/2021) Nucleoprotein / NP Protein
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A purified / Protein G purified
Formulation
Supplied as a 0.22 μm filtered solution of PBS, pH7.4
Application
Application Recommended Usage
ELISA 10~1000ng/mL
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
SDS-PAGE
Influenza A monoclonal antibody(2D6) on SDS-PAGE under reducing (R) and Non-reducing (N-R) condition.
The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
Bioactivity-ELISA
Immobilized Influenza A and Influenza B Nucleoprotein(His Tag) ,at 1μg/mL (100 μL/well) . Binding activity of fluA antibodies.
Background
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral proteins. The nucleoprotein forms large, RNA-bound, helical filaments and acts as a scaffold for additional viral proteins.