Source

Monoclonal Anti-Influenza A Antibody, Mouse IgG1 (2D6) is a Mouse monoclonal antibody expressed from HEK293 

Clone

2D6

Isotype

Mouse IgG1

Conjugate

Unconjugated

Antibody Type

Recombinant Monoclonal

Reactivity

Virus

Immunogen

Influenza A H1N1 (A/Wisconsin/67/2022) Nucleoprotein/NP

Specificity

This product is a specific antibody specifically reacts with Influenza A Nucleoprotein (Influenza A Virus).

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A purified / Protein G purified

Formulation

Supplied as a 0.22 μm filtered solution of  PBS, pH7.4

Application

Application   Recommended Usage

ELISA             1~1000ng/mL

Storage

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Cross Verification         

This product No cross-reactivity in ELISA with Influenza B (B/Austria/1359417/2021) Nucleoprotein / NP Protein 

SDS-PAGE

 2D6

Influenza A monoclonal antibody(2D6) on SDS-PAGE under reducing (R) and Non-reducing (N-R) condition.

The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%

 

Bioactivity-ELISA

2D6对比

Immobilized Influenza A and Influenza B Nucleoprotein(His Tag) ,at 1μg/mL (100 μL/well) . Binding activity of fluA antibodies.

 

Background

Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral proteins. The nucleoprotein forms large, RNA-bound, helical filaments and acts as a scaffold for additional viral proteins.

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